K126T (p.Lys126Thr) variant of IFNGR1 (Interferon gamma receptor 1)
K126T (p.Lys126Thr) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
K126T (p.Lys126Thr) variant details
- p.Lys126Thr
- gnomAD rs1779381835
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.55
- CADD 23.30
- PolyPhen-2 0.96
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available