K109E (p.Lys109Glu) variant of IFNGR1 (Interferon gamma receptor 1)
K109E (p.Lys109Glu) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
K109E (p.Lys109Glu) variant details
- p.Lys109Glu
- ExAC rs780883054
- TOPMed rs780883054
- gnomAD rs780883054
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.09
- CADD 16.60
- PolyPhen-2 0.02
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available