I80M (p.Ile80Met) variant of IFNGR1 (Interferon gamma receptor 1)
I80M (p.Ile80Met) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
I80M (p.Ile80Met) variant details
- p.Ile80Met
- gnomAD rs1196793520
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.45
- CADD 10.70
- PolyPhen-2 0.93
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available