F119L (p.Phe119Leu) variant of IFNGR1 (Interferon gamma receptor 1)
F119L (p.Phe119Leu) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
F119L (p.Phe119Leu) variant details
- p.Phe119Leu
- TOPMed rs1323973607
- gnomAD rs1323973607
- Missense
- Variant Prioritization Score for Impact Estimate 0.537
- REVEL 0.55
- CADD 23.70
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available