D124G (p.Asp124Gly) variant of IFNGR1 (Interferon gamma receptor 1)
D124G (p.Asp124Gly) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
D124G (p.Asp124Gly) variant details
- p.Asp124Gly
- TOPMed rs546121815
- gnomAD rs546121815
- Missense
- Variant Prioritization Score for Impact Estimate 0.379
- REVEL 0.29
- CADD 23.00
- PolyPhen-2 0.03
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available