A76T (p.Ala76Thr) variant of IFNGR1 (Interferon gamma receptor 1)
A76T (p.Ala76Thr) in IFNGR1 (Interferon gamma receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A76T (p.Ala76Thr) variant details
- p.Ala76Thr
- TOPMed rs1026353199
- gnomAD rs1026353199
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.15
- CADD 22.60
- PolyPhen-2 0.70
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available