A2T (p.Ala2Thr) variant of IFNGR1 (Interferon gamma receptor 1)
A2T (p.Ala2Thr) in IFNGR1 (Interferon gamma receptor 1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes structural context.
A2T (p.Ala2Thr) variant details
- p.Ala2Thr
- rs1018508960
- NCI-TCGA Cosmic COSV6298
- Ensembl rs1018508960
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.431
- AlphaMissense 0.25
- MetaLR 0.30
- MetaSVM -0.61
- PolyPhen-2 0.77
- SIFT 0.32
- MutPred 0.55
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available