V22D (p.Val22Asp) variant of IDS (Iduronate 2-sulfatase)
V22D (p.Val22Asp) in IDS (Iduronate 2-sulfatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
V22D (p.Val22Asp) variant details
- p.Val22Asp
- gnomAD rs1557340581
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.60
- CADD 10.00
- PolyPhen-2 0.02
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available