T99I (p.Thr99Ile) variant of IDS (Iduronate 2-sulfatase)
T99I (p.Thr99Ile) in IDS (Iduronate 2-sulfatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
T99I (p.Thr99Ile) variant details
- p.Thr99Ile
- TOPMed rs2089497015
- Missense
- Variant Prioritization Score for Impact Estimate 0.785
- REVEL 0.95
- CADD 26.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available