L41R (p.Leu41Arg) variant of IDS (Iduronate 2-sulfatase)
L41R (p.Leu41Arg) in IDS (Iduronate 2-sulfatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
L41R (p.Leu41Arg) variant details
- p.Leu41Arg
- Ensembl rs2089505287
- Missense
- Variant Prioritization Score for Impact Estimate 0.737
- REVEL 0.87
- CADD 24.40
- PolyPhen-2 0.87
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.9e-05)
- Structural context available