G14R (p.Gly14Arg) variant of IDS (Iduronate 2-sulfatase)
G14R (p.Gly14Arg) in IDS (Iduronate 2-sulfatase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
G14R (p.Gly14Arg) variant details
- p.Gly14Arg
- gnomAD rs1557340590
- Missense
- Variant Prioritization Score for Impact Estimate 0.479
- REVEL 0.52
- CADD 8.38
- PolyPhen-2 0.17
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available