Y38C (p.Tyr38Cys) variant of HLA-DRA (P01903)
Y38C (p.Tyr38Cys) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
Y38C (p.Tyr38Cys) variant details
- p.Tyr38Cys
- TOPMed rs1471176855
- gnomAD rs1471176855
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.11
- CADD 23.20
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available