T66A (p.Thr66Ala) variant of HLA-DRA (P01903)
T66A (p.Thr66Ala) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
T66A (p.Thr66Ala) variant details
- p.Thr66Ala
- gnomAD rs1381520023
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.18
- CADD 24.50
- PolyPhen-2 1.00
- SIFT 0.14
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available