S78I (p.Ser78Ile) variant of HLA-DRA (P01903)
S78I (p.Ser78Ile) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
S78I (p.Ser78Ile) variant details
- p.Ser78Ile
- gnomAD rs1762688867
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.15
- CADD 24.70
- PolyPhen-2 0.77
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available