S23L (p.Ser23Leu) variant of HLA-DRA (P01903)
S23L (p.Ser23Leu) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S23L (p.Ser23Leu) variant details
- p.Ser23Leu
- ExAC rs771937138
- TOPMed rs771937138
- gnomAD rs771937138
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.12
- CADD 19.10
- PolyPhen-2 0.04
- SIFT 0.11
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available