R75* (p.Arg75Ter) variant of HLA-DRA (P01903)
R75* (p.Arg75Ter) in HLA-DRA (P01903) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
R75* (p.Arg75Ter) variant details
- p.Arg75Ter
- rs754420534
- ExAC rs754420534
- TOPMed rs754420534
- gnomAD rs754420534
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.422
- CADD 34.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available