M18L (p.Met18Leu) variant of HLA-DRA (P01903)
M18L (p.Met18Leu) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
M18L (p.Met18Leu) variant details
- p.Met18Leu
- TOPMed rs1033174290
- gnomAD rs1033174290
- Missense
- Variant Prioritization Score for Impact Estimate 0.0998
- REVEL 0.07
- CADD 9.05
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available