L85S (p.Leu85Ser) variant of HLA-DRA (P01903)
L85S (p.Leu85Ser) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
L85S (p.Leu85Ser) variant details
- p.Leu85Ser
- TOPMed rs1219191287
- gnomAD rs1219191287
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.24
- CADD 26.20
- PolyPhen-2 0.72
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available