L70P (p.Leu70Pro) variant of HLA-DRA (P01903)
L70P (p.Leu70Pro) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L70P (p.Leu70Pro) variant details
- p.Leu70Pro
- TOPMed rs1775954101
- gnomAD rs1775954101
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.28
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available