K63E (p.Lys63Glu) variant of HLA-DRA (P01903)
K63E (p.Lys63Glu) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
K63E (p.Lys63Glu) variant details
- p.Lys63Glu
- gnomAD 6-32442552-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.16
- CADD 23.30
- PolyPhen-2 0.49
- SIFT 0.05
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available