I14V (p.Ile14Val) variant of HLA-DRA (P01903)
I14V (p.Ile14Val) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
I14V (p.Ile14Val) variant details
- p.Ile14Val
- ExAC rs750880721
- TOPMed rs750880721
- gnomAD rs750880721
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.04
- CADD 11.20
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available