F73S (p.Phe73Ser) variant of HLA-DRA (P01903)
F73S (p.Phe73Ser) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
F73S (p.Phe73Ser) variant details
- p.Phe73Ser
- ExAC rs760968091
- TOPMed rs760968091
- gnomAD rs760968091
- Missense
- Variant Prioritization Score for Impact Estimate 0.472
- REVEL 0.36
- CADD 25.90
- PolyPhen-2 0.38
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available