F57L (p.Phe57Leu) variant of HLA-DRA (P01903)
F57L (p.Phe57Leu) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
F57L (p.Phe57Leu) variant details
- p.Phe57Leu
- TOPMed rs1374452743
- gnomAD rs1374452743
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.19
- CADD 23.70
- PolyPhen-2 0.17
- SIFT 0.07
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available