F47L (p.Phe47Leu) variant of HLA-DRA (P01903)
F47L (p.Phe47Leu) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
F47L (p.Phe47Leu) variant details
- p.Phe47Leu
- 1000Genomes rs555417043
- TOPMed rs555417043
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.17
- CADD 25.00
- PolyPhen-2 0.43
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available