E22K (p.Glu22Lys) variant of HLA-DRA (P01903)
E22K (p.Glu22Lys) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
E22K (p.Glu22Lys) variant details
- p.Glu22Lys
- gnomAD 6-32440014-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.02
- CADD 12.10
- PolyPhen-2 0.01
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available