A35S (p.Ala35Ser) variant of HLA-DRA (P01903)
A35S (p.Ala35Ser) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
A35S (p.Ala35Ser) variant details
- p.Ala35Ser
- gnomAD 6-32442468-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.10
- CADD 22.20
- PolyPhen-2 0.68
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available