A25V (p.Ala25Val) variant of HLA-DRA (P01903)
A25V (p.Ala25Val) in HLA-DRA (P01903) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
A25V (p.Ala25Val) variant details
- p.Ala25Val
- gnomAD 6-32440024-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.20
- CADD 26.60
- PolyPhen-2 0.96
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available