Y36C (p.Tyr36Cys) variant of HLA-DPB1 (P04440)
Y36C (p.Tyr36Cys) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
Y36C (p.Tyr36Cys) variant details
- p.Tyr36Cys
- gnomAD 6-33080678-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.20
- CADD 19.50
- PolyPhen-2 0.02
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 8.1e-06)
- Structural context available
- Literature evidence available