V3I (p.Val3Ile) variant of HLA-DPB1 (P04440)
V3I (p.Val3Ile) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
V3I (p.Val3Ile) variant details
- p.Val3Ile
- ExAC rs773568820
- TOPMed rs773568820
- gnomAD rs773568820
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.07
- CADD 18.70
- PolyPhen-2 0.34
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available