V21E (p.Val21Glu) variant of HLA-DPB1 (P04440)
V21E (p.Val21Glu) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
V21E (p.Val21Glu) variant details
- p.Val21Glu
- ExAC rs763465797
- gnomAD rs763465797
- Missense
- Variant Prioritization Score for Impact Estimate 0.161
- REVEL 0.14
- CADD 16.70
- PolyPhen-2 0.48
- SIFT 0.00
- Most common in the South Asian population (allele frequency 4.7e-05)
- Structural context available