T50R (p.Thr50Arg) variant of HLA-DPB1 (P04440)
T50R (p.Thr50Arg) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
T50R (p.Thr50Arg) variant details
- p.Thr50Arg
- gnomAD 6-33080720-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.25
- CADD 23.00
- PolyPhen-2 0.45
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available