T24P (p.Thr24Pro) variant of HLA-DPB1 (P04440)
T24P (p.Thr24Pro) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
T24P (p.Thr24Pro) variant details
- p.Thr24Pro
- ExAC rs763726124
- gnomAD rs763726124
- Missense
- Variant Prioritization Score for Impact Estimate 0.0879
- REVEL 0.05
- CADD 8.35
- PolyPhen-2 0.42
- SIFT 0.75
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available