T12S (p.Thr12Ser) variant of HLA-DPB1 (P04440)
T12S (p.Thr12Ser) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
T12S (p.Thr12Ser) variant details
- p.Thr12Ser
- TOPMed rs1200566458
- gnomAD rs1200566458
- Missense
- Variant Prioritization Score for Impact Estimate 0.107
- REVEL 0.09
- CADD 8.13
- PolyPhen-2 0.53
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available