T12P (p.Thr12Pro) variant of HLA-DPB1 (P04440)
T12P (p.Thr12Pro) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
T12P (p.Thr12Pro) variant details
- p.Thr12Pro
- TOPMed rs1200566458
- gnomAD rs1200566458
- Missense
- Variant Prioritization Score for Impact Estimate 0.136
- REVEL 0.12
- CADD 11.50
- PolyPhen-2 0.79
- SIFT 0.11
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available