S25Y (p.Ser25Tyr) variant of HLA-DPB1 (P04440)
S25Y (p.Ser25Tyr) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
S25Y (p.Ser25Tyr) variant details
- p.Ser25Tyr
- gnomAD 6-33076115-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.13
- CADD 22.50
- PolyPhen-2 0.74
- SIFT 0.45
- Population evidence available
- Structural context available
- Literature evidence available