S25F (p.Ser25Phe) variant of HLA-DPB1 (P04440)
S25F (p.Ser25Phe) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
S25F (p.Ser25Phe) variant details
- p.Ser25Phe
- gnomAD 6-33076115-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.07
- CADD 22.80
- PolyPhen-2 0.65
- SIFT 0.37
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available