S25C (p.Ser25Cys) variant of HLA-DPB1 (P04440)
S25C (p.Ser25Cys) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
S25C (p.Ser25Cys) variant details
- p.Ser25Cys
- ExAC rs751203807
- TOPMed rs751203807
- gnomAD rs751203807
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.11
- CADD 22.60
- PolyPhen-2 0.72
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3e-05)
- Structural context available