R41W (p.Arg41Trp) variant of HLA-DPB1 (P04440)
R41W (p.Arg41Trp) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
R41W (p.Arg41Trp) variant details
- p.Arg41Trp
- gnomAD rs1258332221
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.14
- CADD 17.90
- PolyPhen-2 0.09
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available