R41Q (p.Arg41Gln) variant of HLA-DPB1 (P04440)
R41Q (p.Arg41Gln) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
R41Q (p.Arg41Gln) variant details
- p.Arg41Gln
- gnomAD 6-33080693-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.14
- CADD 16.80
- PolyPhen-2 0.12
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available