R41P (p.Arg41Pro) variant of HLA-DPB1 (P04440)
R41P (p.Arg41Pro) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
R41P (p.Arg41Pro) variant details
- p.Arg41Pro
- TOPMed rs41540313
- gnomAD rs41540313
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.20
- CADD 22.50
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available