R30W (p.Arg30Trp) variant of HLA-DPB1 (P04440)
R30W (p.Arg30Trp) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
R30W (p.Arg30Trp) variant details
- p.Arg30Trp
- gnomAD 6-33076129-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.18
- CADD 25.80
- PolyPhen-2 0.76
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available