R11W (p.Arg11Trp) variant of HLA-DPB1 (P04440)
R11W (p.Arg11Trp) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
R11W (p.Arg11Trp) variant details
- p.Arg11Trp
- ExAC rs777782877
- TOPMed rs777782877
- gnomAD rs777782877
- Missense
- Variant Prioritization Score for Impact Estimate 0.0635
- REVEL 0.04
- CADD 2.45
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the HGDP:DRUZE population (allele frequency 0.014)
- Structural context available