R11P (p.Arg11Pro) variant of HLA-DPB1 (P04440)
R11P (p.Arg11Pro) in HLA-DPB1 (P04440) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
R11P (p.Arg11Pro) variant details
- p.Arg11Pro
- rs1048293876
- gnomAD 6-33076066-G-GC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.171
- CADD 12.80
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available