P33S (p.Pro33Ser) variant of HLA-DPB1 (P04440)
P33S (p.Pro33Ser) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P33S (p.Pro33Ser) variant details
- p.Pro33Ser
- TOPMed rs1393414427
- gnomAD rs1393414427
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.11
- CADD 18.50
- PolyPhen-2 0.32
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available