P10S (p.Pro10Ser) variant of HLA-DPB1 (P04440)
P10S (p.Pro10Ser) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
P10S (p.Pro10Ser) variant details
- p.Pro10Ser
- gnomAD 6-33076069-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.123
- REVEL 0.11
- CADD 7.71
- PolyPhen-2 0.76
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available