M2V (p.Met2Val) variant of HLA-DPB1 (P04440)
M2V (p.Met2Val) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
M2V (p.Met2Val) variant details
- p.Met2Val
- gnomAD 6-33076045-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.16
- CADD 0.81
- PolyPhen-2 0.00
- SIFT 0.70
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available