M2I (p.Met2Ile) variant of HLA-DPB1 (P04440)
M2I (p.Met2Ile) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
M2I (p.Met2Ile) variant details
- p.Met2Ile
- TOPMed rs1169806514
- gnomAD rs1169806514
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.16
- CADD 19.80
- PolyPhen-2 0.02
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available