M20T (p.Met20Thr) variant of HLA-DPB1 (P04440)
M20T (p.Met20Thr) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
M20T (p.Met20Thr) variant details
- p.Met20Thr
- ExAC rs770193215
- TOPMed rs770193215
- gnomAD rs770193215
- Missense
- Variant Prioritization Score for Impact Estimate 0.0663
- REVEL 0.03
- CADD 7.06
- PolyPhen-2 0.15
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available