M20I (p.Met20Ile) variant of HLA-DPB1 (P04440)
M20I (p.Met20Ile) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
M20I (p.Met20Ile) variant details
- p.Met20Ile
- ExAC rs376742482
- TOPMed rs376742482
- gnomAD rs376742482
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.08
- CADD 11.80
- PolyPhen-2 0.04
- SIFT 0.16
- Most common in the East Asian population (allele frequency 0.00013)
- Structural context available