L54P (p.Leu54Pro) variant of HLA-DPB1 (P04440)
L54P (p.Leu54Pro) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
L54P (p.Leu54Pro) variant details
- p.Leu54Pro
- TOPMed rs1465711975
- gnomAD rs1465711975
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.16
- CADD 23.80
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available